Domain Areas For Projects

Every year, Amplikon Biosystems opens registrations for Job oriented project/dissertation program for students. During the project, we don’t only train the student in technical skills but we also train them in professional skills so that they can get industrial ready after the completion of their project/dissertation. We also provide 100% placement assistance to our students.

Project Dissertation at Amplikon Biosystems

Your project dissertation is not just a requirement—it’s the first big step into the biotech industry. At Amplikon Biosystems, we ensure that every project is aligned with the latest industrial discoveries and designed to meet global research standards.

Frontier Research Topics (Current Highlights 🚀)

At Amplikon, we bring students directly into the future of biotechnology with projects at the cutting edge of discovery:

Development of Antibody–PROTAC conjugates for HER2-dependent targeted BRD4 degradation in breast cancer.
Design and molecular docking of bifunctional PROTAC-based antibody conjugates for HER2+ cancers.
In silico and wet lab prototype development of antibody–PROTAC conjugates for targeted degradation of mutant huntingtin protein in Huntington’s disease.
Antibody–PROTAC conjugates targeting HPV oncogenic proteins for cervical cancer therapy.
Antibody–PROTAC approaches for tau protein degradation in Alzheimer’s disease.
HER2-targeted CAR-T therapy constructs for breast cancer immunotherapy.
CAR-T based therapy development for hepatocellular carcinoma.
mRNA-based vaccine development for cervical cancer (in silico + in vitro).

Current Ongoing Projects at Amplikon Biosystems

Recombinant & Molecular Biology Projects

Vector designing and cloning of recombinant GFP protein in BL21(DE3) host system.
PETase gene cloning for plastic degradation in E. coli.
Recombinant bacterial clone generation producing nickel-binding protein with GFP tag.
In silico and in vitro development of multiepitope recombinant vaccines to prevent cervical cancer.

Nanoparticle & Therapeutic Applications

Synthesis of gold and silver nanoparticles and evaluation for therapeutic efficacy.
Functionalization of iron oxide nanoparticles with carboxy and silica coatings for biomedical applications.
Sol-gel method optimization for nanoparticle formulations.
Development of bio-based graphene oxide nanoparticles for sustainable lubrication.

Cell Culture & Assay Development

In vitro screening of indename and phenyl methyl derivatives using cancer cell lines.
Macrophage cell line models for rheumatoid arthritis studies with nanoparticle interventions.
Development of ELISA kits for breast cancer detection (CA 15-3) and anti-Rituximab antibody detection.
Optimization of transfection efficiency in HEK cell lines using iron oxide nanoparticle formulations.
Frontier Bioinformatics & AI-Driven Research 🌐

Along with wet-lab projects, we also integrate computational and AI-powered bioinformatics research, which is rapidly transforming biotechnology:
- Epitope-based vaccine designing: In silico prediction of B-cell and T-cell epitopes, followed by validation through cloning and immunoassays.
- Protein structure prediction: Using Google DeepMind’s AlphaFold 3 to understand structural biology at an atomic level.
- Generative AI in protein design: Employing NVIDIA’s atomistic protein prediction tools to simulate folding, stability, and interactions at industrial scale.
- AI in drug discovery: Applying generative models (like those from AAAI research) for novel therapeutic design, molecular docking, and optimization.
Industry Relevance: These computational techniques are becoming indispensable in drug development pipelines, rational vaccine design, precision medicine, and advanced therapeutics like antibody–PROTACs.

Why It Matters for Your Career

One key factor Indian students must consider is:
👉 How will my project affect my future entry into the biotech industry?

At Amplikon Biosystems, your dissertation is designed to:

Provide hands-on training on assays, molecular cloning, nanotech, and immunoassays.
Give you exposure to industry-standard research areas that top pharma and biotech companies are investing in right now.
Build a career advantage for jobs, higher studies, and research publishing.

✨ Following Skills You Will Learn at Amplikon Biosystems Along with Your Master Project/ Dissertation at Amplikon Biosystems

Preparing Biotech Students for the Future Industry

A successful career in biotechnology requires more than just completing a degree—it demands practical skills, industry-level exposure, and hands-on confidence. At Amplikon Biosystems, we believe that every student stepping into their dissertation should also be preparing for their upcoming biotech industry career. That’s why our programs are structured to equip students with a 360° skill set that companies actively look for.

Essential Skills for Biotech Careers

Students aiming to enter the biotech sector should develop expertise across multiple domains:

1. Molecular Biology 🧬

Core Skills: Vector designing, cloning, ligation, transformation, colony screening, PCR, qPCR, sequencing.
Advanced Skills: Handling different cloning vectors (pUC19, pET, pcDNA), expression vectors, and host strains like E. coli DH5α, NEB Stable, and BL21(DE3).
Industry Relevance: Molecular biology forms the foundation of drug discovery, vaccine design, and synthetic biology applications. Companies in pharma, diagnostics, and genetic engineering expect students to be skilled in these techniques.

2. Mammalian Cell Culture 🧫

Core Skills: Culturing HEK293, CHO, and other mammalian cell lines; aseptic handling; cryopreservation; viability assays (Alamar Blue, MTT, Trypan Blue).
Advanced Skills: Transfection and transduction techniques, stable cell line development, in vitro toxicity assays, flow cytometry, cytokine ELISA.
Industry Relevance: Crucial for monoclonal antibody production, CAR-T cell therapy, vaccine development, and drug screening.

3. Upstream Bioprocessing ⚗️

Core Skills: Inoculum preparation, fermentation, protein induction strategies, scale-up from shake flasks to bioreactors.
Advanced Skills: Fed-batch and continuous culture, process parameter optimization (pH, DO, temperature), metabolic flux control.
Industry Relevance: Forms the backbone of industrial biotechnology—from producing therapeutic proteins to large-scale enzyme manufacturing.

4. Downstream Processing 🔬

Core Skills: Protein extraction, purification using precipitation and centrifugation.
Advanced Skills: High-resolution purification using Ni-NTA affinity chromatography, ion exchange chromatography, and size-exclusion chromatography.
Analytical Techniques: SDS-PAGE, Western blotting, HPLC, mass spectrometry for protein characterization.
Industry Relevance: Absolutely vital for biopharma, vaccine production, biosimilars, and enzyme manufacturing industries.

5. Assay Development & Immunotechnology 🧪

Core Skills: ELISA, immunofluorescence, flow cytometry, and immunoprecipitation.
Advanced Skills: Diagnostic kit development, biomarker detection assays, antibody titration assays.
Industry Relevance: Key to clinical diagnostics, personalized medicine, and therapeutic antibody development.

6. Nanobiotechnology & Advanced Therapeutics ⚛️

Core Skills: Synthesis of gold, silver, and iron oxide nanoparticles; characterization using SEM, DLS, and zeta potential.
Advanced Skills: Functionalization with biomolecules (carboxyl, silica, PEGylation), formulation development for drug delivery.
Industry Relevance: Emerging as a strong field in drug delivery systems, imaging agents, biosensors, and next-generation therapeutics like antibody–PROTACs.

Training the Amplikon Way

At Amplikon Biosystems, your project is not limited to one area. Instead, it is designed to integrate multiple industrial skills:

If you work on upstream processing, you won’t just stop at fermentation—you’ll also learn how to induce protein expression, scale-up, purify proteins, and check expression using assays like SDS-PAGE, Western blotting, and ELISA.
If you are in molecular biology, you’ll not only handle PCR and cloning but also work with different expression systems and hosts, giving you confidence to troubleshoot like an industry professional.
If you are in cell culture projects, you’ll learn cytotoxicity assays, cytokine profiling, and real-world screening models used in pharma R&D.

And importantly, we teach you from the scratch:

How to calculate concentrations and molarities accurately.
How to prepare buffers and maintain pH.
How to maintain accuracy and reproducibility in experiments.
How to keep proper lab documentation (GLP/GMP mindset).

This ensures that when you complete your dissertation, you don’t just have a “project report”—you have a full skillset that makes you industry-ready.

Where These Skills Take You in Industry

With the skills you acquire at Amplikon, you can confidently explore careers in:

Pharmaceutical R&D (drug discovery, vaccine development, monoclonal antibodies).
Industrial Biotechnology (fermentation technology, enzyme production, bioprocess scale-up).
Biopharma & CROs (contract research organizations for assays, screening, toxicology).
Diagnostics & Healthcare (ELISA kits, biomarker assays, rapid test development).
Nanomedicine & Advanced Therapeutics (drug delivery, imaging, antibody–PROTACs, CAR-T).
Synthetic Biology & Genetic Engineering (gene editing, recombinant technology, biosynthetic pathways).

✨ At Amplikon Biosystems, we don’t just give you a project—we give you the complete training ecosystem to make you industry-ready from day one.

👉 Apply now and prepare yourself with the skills that the biotech industry demands.